E7046
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
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Catalog Num | A19711 |
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Formula | C22H18F5N3O4 |
Molecular Weight | 483.39 |
CAS Number | 1369489-71-3 |
SMILES | O=C(O)C1=CC=C([C@@H](NC(C2=C(OC3=CC=CC(C(F)(F)F)=C3)N(C)N=C2C(F)F)=O)C)C=C1 |
Synonyms | E-7046; E 7046 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 90 mg/mL (186.18 mM) | |
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.69 mL | 103.44 mL | 206.87 mL |
0.5 mM | 4.14 mL | 20.69 mL | 41.37 mL |
1 mM | 2.07 mL | 10.34 mL | 20.69 mL |
5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2