E722-2648 is a selective inhibitor of the β-catenin/BCL9 complex, targeting the interaction between these two proteins to inhibit β-catenin-mediated transcriptional activity. This compound demonstrates significant antitumor activity by downregulating the expression of WNT target genes, effectively suppressing tumor growth in colon cancer xenograft and colorectal cancer mouse models. E722-2648 serves as a valuable tool for investigating the molecular mechanisms of colon and colorectal cancers.
E722-2648 is a selective inhibitor of the β-catenin/BCL9 complex, targeting the interaction between these two proteins to inhibit β-catenin-mediated transcriptional activity. This compound demonstrates significant antitumor activity by downregulating the expression of WNT target genes, effectively suppressing tumor growth in colon cancer xenograft and colorectal cancer mouse models. E722-2648 serves as a valuable tool for investigating the molecular mechanisms of colon and colorectal cancers.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
