E7766 diammonium salt

Catalog No.: A65553
STING Agonist
E7766 diammonium salt is a macrocycle-bridged STING agonist that exhibits a dissociation constant (Kd) of 40 nM. This compound demonstrates potent pan-genotypic activity and significant antitumor effects, making it a valuable tool for cancer immunotherapy research. It is suitable for studies focused on modulating the STING pathway to enhance immune responses against tumors.
Grouped product items
Size Price Stock Qty
1mg
$465.00
In stock
5mg
$770.00
In stock
10mg
$970.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionE7766 diammonium salt is a macrocycle-bridged STING agonist that exhibits a dissociation constant (Kd) of 40 nM. This compound demonstrates potent pan-genotypic activity and significant antitumor effects, making it a valuable tool for cancer immunotherapy research. It is suitable for studies focused on modulating the STING pathway to enhance immune responses against tumors.
Product Information
Catalog NumA65553
FormulaC24H32F2N12O8P2S2
Molecular Weight780.66
CAS Number2242635-03-4
SMILESF[C@@H]1[C@H](O[P@]2(S)=O)[C@@H](CO[P@]3(S)=O)O[C@H]1[N@]4C5=NC=NC(NC/C=C/CNC6=C(N=C[N@]7[C@@H]8O[C@H](CO2)[C@@H](O3)[C@H]8F)C7=NC=N6)=C5N=C4.N.N
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