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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15374 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 610.45 |
| Formula | C24H27N9O6.2HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1190332-25-2 |
| Synonyms | EB47, EB-47 |
| SMILES code | C1CN(CCN1CC(=O)NC2=CC=CC3=C2CNC3=O)C(=O)C4C(C(C(O4)N5C=NC6=C5N=CN=C6N)O)O.Cl.Cl |
| Chemical Name | 2-(4-((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-carbonyl)piperazin-1-yl)-N-(1-oxoisoindolin-4-yl)acetamide dihydrochloride |
Description |
EB 47 is a potent inhibitor of PARP1 with IC50 of 45 nM. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.38 mL | 81.91 mL | 163.81mL |
| 0.5 mM | 3.28 mL | 16.38 mL | 32.76 mL |
| 1 mM | 1.64 mL | 8.19 mL | 16.38 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.28 mL |
*The above data is based on the productmolecular weight 610.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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