Ecopladib is a selective inhibitor of cytosolic phospholipase A2α (cPLA2α), exhibiting sub-micromolar potency with IC50 values of 0.15 μM and 0.11 μM in GLU micelle and rat whole blood assays, respectively. This compound effectively modulates the release of arachidonic acid and subsequent eicosanoid synthesis, making it a valuable tool for studying inflammatory processes. Ecopladib is applicable in research focused on the mechanisms of inflammation and related pathways.
Ecopladib is a selective inhibitor of cytosolic phospholipase A2α (cPLA2α), exhibiting sub-micromolar potency with IC50 values of 0.15 μM and 0.11 μM in GLU micelle and rat whole blood assays, respectively. This compound effectively modulates the release of arachidonic acid and subsequent eicosanoid synthesis, making it a valuable tool for studying inflammatory processes. Ecopladib is applicable in research focused on the mechanisms of inflammation and related pathways.
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