EF-1502 is a selective inhibitor of GABA transporters, specifically targeting GAT1 and BGT1. This compound demonstrates significant anti-epileptic activity, especially when combined with Tiagabine, enhancing seizure suppression. In contrast, co-administration with THIP resulted in reduced efficacy and dyskinesia, indicating a distinct mechanism of action. EF-1502 thus serves as a valuable tool for research into GABAergic modulation and its implications in epilepsy treatment strategies.
EF-1502 is a selective inhibitor of GABA transporters, specifically targeting GAT1 and BGT1. This compound demonstrates significant anti-epileptic activity, especially when combined with Tiagabine, enhancing seizure suppression. In contrast, co-administration with THIP resulted in reduced efficacy and dyskinesia, indicating a distinct mechanism of action. EF-1502 thus serves as a valuable tool for research into GABAergic modulation and its implications in epilepsy treatment strategies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
