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Elcatonin (Carbocalcitonin)

Catalog No.: A98871
Drug Intermediate
Elcatonin, a synthetic analog of eel calcitonin, functions as a drug intermediate with significant implications in bone metabolism. It is known to increase bone mineral density and inhibit bone resorption, making it valuable in research related to osteoporosis and bone health. Additionally, Elcatonin exhibits central analgesic effects, thereby supporting applications in pain management studies.
Elcatonin (Carbocalcitonin) 60731-46-6 Drug Intermediate
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionElcatonin, a synthetic analog of eel calcitonin, functions as a drug intermediate with significant implications in bone metabolism. It is known to increase bone mineral density and inhibit bone resorption, making it valuable in research related to osteoporosis and bone health. Additionally, Elcatonin exhibits central analgesic effects, thereby supporting applications in pain management studies.
Product Information
Catalog NumA98871
FormulaC148H244N42O47
Molecular Weight3363.77
CAS Number60731-46-6
SequenceSer-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Lactam bridge: Ser1-Asu6)
Sequence shorteningSNLST{Asu}VLGKLSQELHKLQTYPRTDVGAGTP-NH2 (Lactam bridge: Ser1-Asu6)
SMILESC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(=O)[C@H]3NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CCCCC3)[H])[C@H](C)C)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CO)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CCC(N)=O)=O)[C@@H](C)O)=O)(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(=O)N5[C@H](C(N)=O)CCC5)[C@@H](C)O)=O)=O)C)=O)=O)C(C)C)=O)CC(O)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC4
SynonymsCarbocalcitonin
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