Catalog No.
Product Name
Application
Product Information
Citations
-
Drug Intermediate
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide serves as an essential drug intermediate in the synthesis of diverse bioactive molecules. This compound's structural framework enables exploration in medicinal chemistry and drug development, facilitating the creation of therapeutically relevant agents. Researchers utilize this intermediate to optimize pharmacological properties and enhance biological activity across various applications. -
Drug Intermediate
Camphorsulfonate sodium functions as an organic synthesis intermediate with significant utility in the development of derivatives exhibiting succinate dehydrogenase (SDH) inhibitory activity through scaffold hopping. Additionally, it serves as an organocatalyst, effectively modulating the porosity of graphene films as a pore-forming additive. This compound is valuable in research applications focused on binder-free porous graphene films and fungicide development. -
Drug Intermediate
Kanjone is a chemical intermediate derived from Millettia peguensis, primarily utilized in the synthesis of protein tyrosine phosphatase 1B (PTP1B) inhibitors. This compound exhibits potential therapeutic implications for the study of diabetes and neurological disorders, facilitating research into the modulation of PTP1B activity. Its application serves as a valuable tool in advancing understanding of metabolic regulation and neurodegenerative diseases. -
Drug Intermediate
CCT-010354 is a chemical intermediate utilized in the synthesis of PPARα/δ dual agonists. This compound plays a key role in the development of therapeutics targeting metabolic disorders and inflammatory diseases, where modulation of peroxisome proliferator-activated receptors (PPARs) is beneficial. Its application in drug development underscores its significance in pharmaceutical research. -
Drug Intermediate
2,4-Dihydroxybenzaldehyde serves as a drug intermediate with applications in the synthesis of various Schiff base compounds. This compound demonstrates notable anti-angiogenic, anti-inflammatory, and analgesic activities, attributed to its ability to inhibit the expression of iNOS and COX-2, thus reducing the production of nitric oxide and reactive oxygen species. It is widely utilized in research focused on inflammatory conditions, contributing to the understanding of mechanisms underlying these diseases. -
Linker-drug Intermediate
MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin functions as a linker-drug intermediate in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the conjugation of therapeutic agents with monoclonal antibodies, enhancing targeted delivery to cancer cells. Its application is crucial for research in developing novel ADCs to improve the efficacy and safety of cancer treatments. -
Drug Intermediate
ProX1-(SS)-DOTAGA_R is a drug intermediate designed for targeted radionuclide delivery. It specifically facilitates the localization of therapeutic agents to diseases characterized by ACP3 expression. This compound is instrumental in advancing radiopharmaceutical research and developing precision medicine strategies. -
Drug Intermediate
ProX1-(SS)-DOTAGA is a drug intermediate designed for targeted delivery in therapeutic applications. This compound specifically facilitates the transport of radionuclides, enhancing localization to diseases characterized by the expression of ACP3. Its utility in targeting and delivering therapeutic agents makes it a valuable tool in the development of precision medicine strategies. -
Drug Intermediate
BC-NH2 is a chemical intermediate primarily utilized in pharmaceutical research and development. It serves as a key building block for synthesizing functional marker substrates, facilitating studies in various biological and chemical applications. This compound is essential for advancing drug discovery and development. -
Drug Intermediate
BG-NH2 is a versatile pharmaceutical intermediate that serves as a key building block in the synthesis of fluorescent SNAP tag substrates. This compound is particularly useful for labeling RNA in various experimental settings, facilitating molecular studies and enhancing visualization techniques in biochemical research. BG-NH2’s unique properties make it an essential reagent for applications in drug development and molecular biology. -
Drug Intermediate
3,3-Dimethylacrylic acid is a key intermediate in the synthesis of various pharmaceutical compounds. This small molecule is utilized in the development of drugs, particularly in the creation of polymers and other materials due to its unique structural features. Its versatility as a building block makes it an important reagent in chemical research and drug development applications. -
Drug Intermediate
1,3-Dihydroxyacetone (DHA) serves as an essential drug intermediate and is primarily recognized for its role in sunless tanning skin-care formulations. It is produced industrially through the microbial fermentation of glycerol, particularly using Gluconobacter oxydans. Additionally, 1,3-Dihydroxyacetone is valuable in the synthesis of novel biodegradable polymers when reacted with lactic acid, enhancing its utility in various biochemical and material science applications. -
Drug Intermediate
FI-3 is a polycyclic tetramate macrolactam that serves as a critical biosynthetic intermediate derived from Streptomyces sp. SPB78. It exhibits potential antibiotic properties, making it valuable for research in antibacterial development and biochemical pathways related to antibiotic biosynthesis. -
Drug Intermediate
Propoxybenzene, also known as propyl phenyl ether, serves as a valuable dialkoxybenzene intermediate in chemical synthesis. This compound exhibits antiparasitic activity, making it particularly relevant in research focused on the control of Varroa mite infestations in apiculture. Its unique properties facilitate investigations into effective treatments for parasitic diseases affecting honeybee colonies. -
Drug Intermediate
2'-Hydroxybiphenyl-3-carboxylic acid serves as a β-lactamase OXA-48 inhibitor, with an IC50 value of 50 µM and a Kd of 1750 µM. This compound is primarily utilized as a drug intermediate in the synthesis of therapeutics targeting antibiotic resistance. Its inhibitory properties make it valuable in studying the mechanisms and effects of β-lactamase enzymes in various biological contexts. -
Drug Intermediate
L-erythro-Chloramphenicol is a potent inhibitor of electron transport, primarily targeting mitochondrial function. Its significant biological activity makes it an important reagent in biochemical research relating to mitochondrial pathways and cellular respiration. This compound serves as a valuable intermediate in the synthesis of pharmaceutical agents and investigations involving antibiotic activity. -
Drug Intermediate
2,4-Dichlorothieno[3,2-d]pyrimidine is a thienopyrimidine scaffold recognized as a crucial synthetic intermediate. It plays a significant role in the synthesis of 4-arylthieno[3,2-d]pyrimidine compounds, particularly in the development of human adenosine A2a receptor antagonists and PI3K-α inhibitors. Additionally, this compound shows potential for application in research related to whipworm disease, making it valuable for various biomedical investigations. -
Drug Intermediate
Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes. -
Drug Intermediate
Org-9768, a derivative of (2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine, serves as a chemical intermediate for the synthesis of mitochondrial permeability transition pore (mPTP) inhibitors. Its potential applications encompass investigations into neurological and cardiovascular disorders, particularly in the context of Parkinson's disease research. The compound is instrumental in exploring therapeutic strategies aimed at modulating mitochondrial function and mitigating disease progression. -
Drug Intermediate
m-Tolylacetic acid, also known as 3-Methylbenzeneacetic acid, serves as a hydroaromatic dicarboxylic acid and is commonly found as a metabolite of tolueneacetic acid in urine. This compound is primarily utilized as a drug intermediate, facilitating the synthesis of more complex organic molecules in pharmaceutical research. Its unique structure makes it a valuable component in the development of various bioactive compounds. -
Drug intermediate
4-Methoxybenzenecarbothioamide is a synthetic intermediate primarily employed in pharmaceutical synthesis. This compound is synthesized through the reaction of 4-methoxybenzamide with phosphorus pentasulfide, facilitating the creation of various thioamide derivatives. Its unique structure and reactivity make it a valuable building block for the development of biologically active molecules in chemical research. -
Drug Intermediate
Memantine lactose adduct is a key intermediate in the synthesis of adamantane amine antibiotics. This compound is derived from the reaction of Memantine with lactose, facilitating the development of novel therapeutic agents. Its role in the production of antibiotic compounds makes it valuable for biological research and pharmaceutical applications. -
Drug Intermediate
SOS1 Ligand Intermediate-7 is a critical chemical intermediate utilized in the synthesis of the SOS1 ligand, an important modulator of cellular signaling pathways. This compound plays a significant role in the production of PROTAC SOS1 degrader-1, facilitating targeted protein degradation research. Its applications extend to studies involving SOS1 activation and its implications in various biological processes. -
Drug Intermediate
1,2-Dilignoceroyl-sn-glycero-3-phosphocholine (DLiPC) is a long-chain diacyl phospholipid featuring C24 saturated hydrocarbon chains. As a crucial drug intermediate, it plays a vital role in the synthesis of eicosanoids, which are important mediators in various physiological processes. DLiPC is utilized in biochemical research to study lipid metabolism and cell signaling pathways. -
Drug Intermediate
Dihydridotetrakis(triphenylphosphine)ruthenium(II) serves as an effective catalyst primarily targeting organic synthesis. This compound is particularly notable for its catalytic activity in hydrogenation and dehydrogenation reactions. Its efficiency has garnered significant interest in the research of metal catalysts, positioning it as a valuable reagent for advancing studies in catalysis and synthetic chemistry applications. -
Drug Intermediate
Nickel octaethylporphyrin primarily serves as a drug intermediate by incorporating nickel ions into porphyrin structures. Its unique coordination properties make it valuable for various research applications, including catalysis, photodynamic therapy, and the development of biosensors. The compound's ability to stabilize different oxidation states enhances its utility in synthetic organic chemistry and material science. -
Drug Intermediate
(1,5-Cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate serves as a highly efficient catalyst for hydrogenation reactions. This complex exhibits remarkable activity in facilitating the conversion of hydrogen and organic substrates, making it a valuable reagent for the synthesis of key chemical intermediates. Its application extends to various fields of organic chemistry, contributing to the development of pharmaceuticals and fine chemicals. -
Drug Intermediate
Apixaban ethyl ester is a critical intermediate in the synthesis of factor Xa (FXa) inhibitors. It plays a significant role in studying the inhibitory activity against venous thrombosis. This reagent is essential for researchers focused on anticoagulant drug development and understanding the mechanisms of thrombin inhibition. -
Drug Intermediate
Diphenyl disulfide is a notable drug intermediate that serves as a versatile building block in organic synthesis. Its primary mechanism involves the formation of disulfide bonds, facilitating the coupling with aryl iodides to produce asymmetric aryl sulfides. This compound is widely utilized in medicinal chemistry for the development of new pharmaceutical agents and in various research applications focused on sulfur-containing compounds. -
Drug Intermediate
Tetrakis(acetonitrile)palladium(II) tetrafluoroborate serves as a potent Lewis acid, facilitating the formation of 2:1 complexes, particularly [Pd(1,2-bis(2′-pyridylethynyl)benzene)2](BF4)2. This reagent is primarily utilized in the Sonogashira cross-coupling reaction, making it valuable for synthesizing carbon-carbon bonds in organic chemistry. Its applicability in drug intermediate synthesis underscores its significance in pharmaceutical research and development. -
Drug Intermediate
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde serves as a chiral intermediate in organic synthesis, facilitating the construction of complex molecular architectures. Its chiral properties contribute to potential catalytic applications, making it valuable in the development of novel compounds. Additionally, this compound has demonstrated biocompatibility, further expanding its utility in research involving drug delivery systems. -
Drug Intermediate
Tetrahydrothiophen-3-one is a versatile pharmaceutical intermediate that serves as a precursor in the synthesis of thiazole compounds. This compound is recognized for its role as an endogenous metabolite and is commonly found in various natural food sources. Its favorable safety profile makes it an attractive option for research applications in drug development and chemical synthesis. -
Drug Intermediate
5-Methoxyindole is an indole derivative that serves as a crucial intermediate in drug synthesis. It is primarily utilized to produce compounds such as 5-methoxytryptophan and N-acetyl 5-methoxytryptamine. This compound demonstrates significant anti-cancer and anti-inflammatory activities, making it relevant for research in oncology and inflammation-related studies. -
Drug Intermediate
D-Threonine is an important unnatural amino acid primarily utilized as a chiral building block in pharmaceutical synthesis. As a metabolite of Saccharomyces cerevisiae, it plays a crucial role in various biochemical pathways. D-Threonine can be enzymatically cleaved by D-threonine aldolase to yield glycine and acetaldehyde, highlighting its potential in drug development and metabolic research applications. -
Drug Intermediate
Sodium malonate is a key drug intermediate utilized in the synthesis of various bioactive compounds. It serves as a versatile building block in organic synthesis, particularly in the preparation of carboxylic acids and esters. Its applications extend to pharmaceuticals and agrochemicals, facilitating the development of new therapeutic agents and agricultural products. -
Drug Intermediate
Allyl-mannose-6-phosphonate is a stable analogue of mannose-6-phosphate, serving as a valuable drug intermediate. This compound facilitates the synthesis of M6P-peptide conjugates and the development of lysosome-targeting chimeras (LYTAC), making it essential in various bioconjugation research applications. Its unique properties enable advancements in targeted drug delivery systems and lysosomal targeting strategies in biomedical research. -
Drug Intermediate
6-Ketoestradiol serves as a vital drug intermediate in the synthesis of re-containing 7α-substituted estradiol complexes. Its unique chemical structure allows for the modification of estradiol, facilitating the development of novel compounds with potential therapeutic applications. This reagent is essential for researchers focused on steroid chemistry and the exploration of estrogen-related pathways. -
Drug Intermediate
(4S)-1-Boc-4-fluoro-D-proline is a fluorinated proline derivative that serves as a versatile drug intermediate. Its unique structure allows for the synthesis of various bioactive compounds, making it a valuable reagent in medicinal chemistry and pharmaceutical research. Applications include the development of novel therapeutics and the exploration of proline-based molecular frameworks in drug discovery. -
Synthetic Intermediate
Benzyl piperazine-1-carboxylate is a synthetic intermediate primarily utilized in the development of melanocortin-4 (MC4) receptor antagonists. Its structural properties make it valuable in biochemical research aimed at understanding and modulating MC4 receptor activity, which is implicated in various physiological processes including appetite regulation and energy homeostasis. This compound serves as a critical building block for the synthesis of novel therapeutic candidates targeting the MC4 receptor. -
Drug Intermediate
3-Butenoic acid, a versatile drug intermediate, serves as a key building block in the synthesis of bicyclic 3,6-dihydro-1,2-oxazine. This strained bicyclic compound is a reactive substrate utilized in domino metathesis reactions in conjunction with external alkenes. Its unique properties make it valuable for chemical research and the development of innovative therapeutic agents. -
Drug Intermediate
1-Bromo-3-iodobenzene is a versatile organic synthetic intermediate that plays a critical role in chemical research. Acting as a halogenated benzene derivative, it is frequently employed in the synthesis of various active compounds and complex organic molecules. This reagent is valuable for researchers looking to develop new pharmaceuticals or other biologically active substances. -
Drug Intermediate
D-Glucurono-6,3-lactone acetonide is an acetone-protected derivative of D-Glucurono-6,3-lactone, serving as a valuable synthetic intermediate in chemical research. This compound facilitates the synthesis of various glucuronides and can be instrumental in drug development and metabolic studies. Its unique protective group allows for enhanced reactivity in synthetic pathways, making it an important tool for chemists exploring glycosylation and related reactions. -
Drug Intermediate
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a versatile drug intermediate that facilitates the synthesis of kinase inhibitors targeting Cdk4, PDGF, FGF, and EGF pathways. This compound exhibits significant potential in medicinal chemistry and pharmaceutical research, contributing to the development of therapies aimed at regulating cell proliferation and differentiation. Its structural versatility makes it a valuable building block for the design of innovative drug candidates. -
Drug Intermediate
2-Methyl-1,3-cyclohexanedione is a versatile drug intermediate utilized in synthetic chemistry. Its unique structural properties make it suitable for the development of various pharmaceuticals and therapeutic agents. Additionally, this compound has applications in the cosmetics industry, where it may serve as a key ingredient in formulations. -
Drug Intermediate
Ethyl (E)-3-(1-pyrrolidinyl)crotonate is a versatile enamine ester that serves as a valuable organic synthetic intermediate. Its stable structure combined with significant reactivity facilitates the synthesis of heterocyclic compounds and various drug molecules. This compound is essential for researchers focusing on drug development and the exploration of novel therapeutic agents. -
Drug Intermediate
Diacetone-D-mannitol is a versatile drug intermediate that functions as a protective agent for hydroxyl groups in various organic synthesis applications. It is utilized in the preparation of pharmaceutical compounds and in the development of drug formulations. This compound serves as an essential building block, facilitating the synthesis of more complex molecules in medicinal chemistry research. -
Drug Intermediate
(R)-3-Fluoropyrrolidine hydrochloride serves as a crucial intermediate in chemical synthesis. It is notably utilized in the development of hVanin-1 inhibitors, such as Compound X20. This compound plays a significant role in research related to inflammatory bowel disease, facilitating investigations into therapeutic potentials in this area. -
Drug Intermediate
(S)-Tetrahydrofuran-3-ylamine is a synthetic intermediate primarily utilized in pharmaceutical synthesis. It serves as a valuable building block for the development of various drug compounds. Its unique structural properties enhance its applicability in creating complex molecular architectures necessary for drug discovery and development. -
Drug Intermediate
Ethyl 4-methyl-2-(2-thienyl)-thiazole-5 carboxylate is a synthetic intermediate primarily utilized in pharmaceutical synthesis. Its unique thiazole and thienyl structure make it a valuable building block for the development of various pharmacologically active compounds. This reagent is essential for researchers exploring novel drug formulations and mechanisms of action in drug discovery. -
Drug Intermediate
4-Biphenylthio carboxamide is a synthetic compound utilized primarily as a drug intermediate in pharmaceutical synthesis. This compound serves as a critical building block for the development of various bioactive molecules. Its versatility allows for use in diverse applications within medicinal chemistry and drug discovery.
