Elebsiran is a small interfering RNA (siRNA) that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. This agent significantly reduces HBV surface antigen (HBsAg) levels and viral load, indicating its potent antiviral activity. By binding to the asialoglycoprotein receptor (ASGPR) on liver cells via the GalNAc ligand, Elebsiran enables liver-targeted delivery while ensuring improved liver safety. This reagent is valuable for research focused on chronic HBV and HDV infections.
Elebsiran is a small interfering RNA (siRNA) that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. This agent significantly reduces HBV surface antigen (HBsAg) levels and viral load, indicating its potent antiviral activity. By binding to the asialoglycoprotein receptor (ASGPR) on liver cells via the GalNAc ligand, Elebsiran enables liver-targeted delivery while ensuring improved liver safety. This reagent is valuable for research focused on chronic HBV and HDV infections.
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