Eliglustat tartrate

Catalog No.: A15466

Glucocerebroside synthase inhibitor

Eliglustat tartrate

Eliglustat tartrate Chemical Structure

CAS NO. 928659-70-5

Commonly used as the tartrate salt, Eliglustat is believed to work by inhibition of glucosylceramide synthase.

Availability: In stock

Package Price Qty
5 mg
$180.00
10 mg
$320.00
25 mg
$650.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Zunke F, .et al. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide, Neuron, 2018, Jan 3;97(1):92-107.e10 PMID: 29290548

Biological Activity

Commonly used as the tartrate salt, Eliglustat is believed to work by inhibition of glucosylceramide synthase.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.43 mL 52.13 mL 104.26 mL
0.5 mM 2.09 mL 10.43 mL 20.85 mL
1 mM 1.04 mL 5.21 mL 10.43 mL
5 mM 0.21 mL 1.04 mL 2.09 mL

*The above data is based on the productmolecular weight 959.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15466
Actions Inhibitor
CAS No. 928659-70-5
Formula C50H78N4O14
M. Wt 959.17
Solubility DMSO
Purity >98%
Synonyms GENZ-112638
SMILES CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.C(C(C(=O)O)O)(C(=O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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