Glucosylceramide Synthase

Eliglustat is a specific and potent inhibitor of glucosylceramide synthase.

Miglustat hydrochloride is an orally active α-glucosidase I and II and ceramide-specific glycosyltransferase inhibitor.

Commonly used as the tartrate salt, Eliglustat is believed to work by inhibition of glucosylceramide synthase.

Ibiglustat (Venglustat), a potential therapy for PD Parkinson??s disease, SRT in Fabry??s and Gaucher??s, is a selective, allosteric inhibitor of glucosylceramide synthase (GCS) with ability to cross the blood-brain barrier.

Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor.