ELR510444

Catalog No.: A15455

Microtubule Disruptor

ELR510444

ELR510444 Chemical Structure

CAS NO. 1233948-35-0

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.

Availability: In stock

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10 mg

Regular Price: $120.00

Special Price $96.00

25 mg

Regular Price: $250.00

Special Price $200.00

50 mg

Regular Price: $450.00

Special Price $360.00

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Biological Activity

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.
In vitro DMSO 72 mg/mL (195.4 mM)
Water Insoluble
Ethanol 24 mg/mL (65.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.14 mL 135.7 mL 271.39 mL
0.5 mM 5.43 mL 27.14 mL 54.28 mL
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15455
CAS No. 1233948-35-0
Formula C19H16N2O2S2
M. Wt 368.47
Purity >98%
Synonyms ELR-510444, ELR 510444
SMILES CC1=CC=C(S(NC2=C(C=CC(C3=CC=C(S3)C#N)=C2)C)(=O)=O)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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