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ELR510444

Microtubule Disruptor

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Catalog No. A15455

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ELR510444 10mg A15455-10
$120.00
ELR510444 25mg A15455-25
$250.00
ELR510444 50mg A15455-50
$450.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.

ELR510444

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Chemical Information

Catalog Num A15455
Actions No
M. Wt 368.47
Formula C19H16N2O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1233948-35-0
Synonyms ELR-510444, ELR 510444
SMILES CC1=CC=C(S(NC2=C(C=CC(C3=CC=C(S3)C#N)=C2)C)(=O)=O)C=C1

Biological Activity

Description
ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.14 mL 135.7 mL 271.39mL
0.5 mM 5.43 mL 27.14 mL 54.28 mL
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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