ELR510444

Catalog No.: A15455

Microtubule Disruptor

ELR510444

ELR510444 Chemical Structure

CAS NO. 1233948-35-0

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$450.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.14 mL 135.7 mL 271.39 mL
0.5 mM 5.43 mL 27.14 mL 54.28 mL
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15455
Actions No
M. Wt 368.47
Formula C19H16N2O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1233948-35-0
Synonyms ELR-510444, ELR 510444
SMILES CC1=CC=C(S(NC2=C(C=CC(C3=CC=C(S3)C#N)=C2)C)(=O)=O)C=C1

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