Eniluracil

Catalog No.: A21548

dihydropyrimidine dehydrogenase inhibitor

Eniluracil

Eniluracil Chemical Structure

CAS NO. 59989-18-3

Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity.

Availability: In stock

Package Price Qty
10 mg
$45.00
25 mg
$90.00
50 mg
$155.00
100 mg
$265.00
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Biological Activity

Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 73.47 mL 367.35 mL 734.7 mL
0.5 mM 14.69 mL 73.47 mL 146.94 mL
1 mM 7.35 mL 36.73 mL 73.47 mL
5 mM 1.47 mL 7.35 mL 14.69 mL

*The above data is based on the productmolecular weight 136.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21548
Actions Inhibitor
CAS No. 59989-18-3
Formula C6H4N2O2
M. Wt 136.11
Purity >98%
Synonyms 5-Ethynyluracil; GW776C85, GW 776C85, GW-776C85
SMILES O=C(N1)NC=C(C#C)C1=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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