Enoximone is a selective, orally active phosphodiesterase III (PDE3) inhibitor, exhibiting an IC50 of 5.9 μM. By inhibiting cGMP-inhibited PDE, it promotes vasodilation and elevates intracellular cAMP levels. Additionally, Enoximone demonstrates PDE4 inhibitory effects, with an IC50 of 21.1 μM for myocardial PDE4A. This compound is of significant interest for research into congestive heart failure, as well as for its potential bronchodilatory, antiasthma, and anti-inflammatory properties.
Enoximone is a selective, orally active phosphodiesterase III (PDE3) inhibitor, exhibiting an IC50 of 5.9 μM. By inhibiting cGMP-inhibited PDE, it promotes vasodilation and elevates intracellular cAMP levels. Additionally, Enoximone demonstrates PDE4 inhibitory effects, with an IC50 of 21.1 μM for myocardial PDE4A. This compound is of significant interest for research into congestive heart failure, as well as for its potential bronchodilatory, antiasthma, and anti-inflammatory properties.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
