Biological Activity
Ensartinib hydrochloride (X-396 hydrochloride) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 15.76 mL | 78.82 mL | 157.64 mL |
0.5 mM | 3.15 mL | 15.76 mL | 31.53 mL |
1 mM | 1.58 mL | 7.88 mL | 15.76 mL |
5 mM | 0.32 mL | 1.58 mL | 3.15 mL |
*The above data is based on the productmolecular weight 634.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21719 |
---|---|
Actions | Inhibitor |
M. Wt | 634.36 |
Formula | C26H29Cl4FN6O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2137030-98-7 |
Synonyms | X-396 hydrochloride, X 396, X396 |
SMILES | O=C(C1=NN=C(N)C(O[[email protected]@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1)NC3=CC=C(C(N4C[[email protected]@H](C)N[[email protected]@H](C)C4)=O)C=C3.[2HCl] |
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