Envometinib

Catalog No.: A65812
MEK Inhibitor
Envometinib is a dual MEK inhibitor that utilizes Deep Cyclic Inhibition (DCI) as its primary mechanism of action. It demonstrates significant antitumor activity across various in vivo models, making it a valuable tool for cancer research. Envometinib is particularly relevant for studies involving RAS and RAF mutated cancers, such as colorectal cancer and melanoma.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEnvometinib is a dual MEK inhibitor that utilizes Deep Cyclic Inhibition (DCI) as its primary mechanism of action. It demonstrates significant antitumor activity across various in vivo models, making it a valuable tool for cancer research. Envometinib is particularly relevant for studies involving RAS and RAF mutated cancers, such as colorectal cancer and melanoma.
Product Information
Catalog NumA65812
FormulaC23H27ClN4O6S
Molecular Weight523.00
CAS Number2952542-22-0
SMILESCN(CC(C1=C(OC2=O)C=C(OC(N(C)C)=O)C=C1)=C2CC3=C(C(NS(NC)(=O)=O)=CC=C3)Cl)C
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