EPI-7170 is a potent androgen receptor (AR) antagonist that targets the N-terminal structural domain of the receptor. It effectively inhibits the transcriptional activity of full-length androgen receptor (FL-AR) and its splice variants, providing therapeutic potential against enzalutamide-resistant castration-resistant prostate cancer (CRPC). This compound is valuable for research into mechanisms of resistance in prostate cancer and the development of novel therapeutic strategies.
EPI-7170 is a potent androgen receptor (AR) antagonist that targets the N-terminal structural domain of the receptor. It effectively inhibits the transcriptional activity of full-length androgen receptor (FL-AR) and its splice variants, providing therapeutic potential against enzalutamide-resistant castration-resistant prostate cancer (CRPC). This compound is valuable for research into mechanisms of resistance in prostate cancer and the development of novel therapeutic strategies.
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