Epirubicin

Catalog No.: A12409

Topoisomerase inhibitor

Epirubicin

Epirubicin Chemical Structure

CAS NO. 56420-45-2

Epirubicin is a cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin that exhibits reduced cardiotoxicity. Epirubicin’s antitumor actions are mediated by targeting and inhibiting Topo II (topoisomerase II).

Availability: In stock

Package Price Qty
10 mg
$75.00
25 mg
$150.00
50 mg
$260.00
100 mg
$480.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Xiu-wu Pan, .et al. Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy, Oncol Rep, 2016, Jan;35(1):334-42 PMID: 26496799

Biological Activity

Epirubicin is a cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin that exhibits reduced cardiotoxicity. Epirubicin’s antitumor actions are mediated by targeting and inhibiting Topo II (topoisomerase II).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.99 mL 183.99 mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12409
Actions Inhibitor
CAS No. 56420-45-2
Formula C27H29NO11
M. Wt 543.52
Purity >98%
SMILES C[[email protected]]1[[email protected]@H]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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