Episilvestrol

Catalog No.: A15080

Apoptosis inducer

Episilvestrol

Episilvestrol Chemical Structure

CAS NO. 697235-39-5

Episilvestrol is a derivative of Silvestrol, which can induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7; 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM).

Availability: In stock

Package Price Qty
0.5 mg
$250.00
1 mg
$360.00
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Biological Activity

Episilvestrol is a derivative of Silvestrol, which can induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7; 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.28 mL 76.38 mL 152.75 mL
0.5 mM 3.06 mL 15.28 mL 30.55 mL
1 mM 1.53 mL 7.64 mL 15.28 mL
5 mM 0.31 mL 1.53 mL 3.06 mL

*The above data is based on the productmolecular weight 654.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15080
Actions Inducer
CAS No. 697235-39-5
Formula C34H38O13
M. Wt 654.66
Purity >98%
SMILES COC1C(OC(CO1)C(CO)O)OC2=CC(=C3C(=C2)OC4(C3(C(C(C4C5=CC=CC=C5)C(=O)OC)O)O)C6=CC=C(C=C6)OC)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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