ER Degrader 12 is an estrogen receptor (ER) degrader with demonstrated IC50 values of 2.3 nM for ERα and 80.2 nM for ERβ, as shown in TR-FRET assays. This compound effectively inhibits the proliferation of MCF-7 breast cancer cells, exhibiting an IC50 of 1.53 nM. ER Degrader 12 is primarily utilized in research applications focused on understanding breast cancer biology and therapeutic strategies targeting estrogen signaling pathways.
ER Degrader 12 is an estrogen receptor (ER) degrader with demonstrated IC50 values of 2.3 nM for ERα and 80.2 nM for ERβ, as shown in TR-FRET assays. This compound effectively inhibits the proliferation of MCF-7 breast cancer cells, exhibiting an IC50 of 1.53 nM. ER Degrader 12 is primarily utilized in research applications focused on understanding breast cancer biology and therapeutic strategies targeting estrogen signaling pathways.
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