ERβ agonist-2 is a selective agonist for estrogen receptor beta (ERβ), exhibiting an EC50 of 800 nM or lower. It effectively inhibits T cell activation and proliferation, leading to a reduction in circulating T cell levels, while sparing neutrophils, monocytes, and B cells. This compound is relevant for research applications related to chronic heart failure post-myocardial infarction, as well as in studies of graft-versus-host disease, multiple sclerosis, and experimental autoimmune encephalomyelitis.
ERβ agonist-2 is a selective agonist for estrogen receptor beta (ERβ), exhibiting an EC50 of 800 nM or lower. It effectively inhibits T cell activation and proliferation, leading to a reduction in circulating T cell levels, while sparing neutrophils, monocytes, and B cells. This compound is relevant for research applications related to chronic heart failure post-myocardial infarction, as well as in studies of graft-versus-host disease, multiple sclerosis, and experimental autoimmune encephalomyelitis.
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