Erlotinib-d6 hydrochloride is a deuterium-labeled inhibitor of the epidermal growth factor receptor (EGFR) kinase, demonstrating potent inhibition with an IC50 of 2 nM. This compound serves as a valuable tool in chemical research, particularly in the study of EGFR-related signaling pathways in cancer. Additionally, Erlotinib-d6 hydrochloride features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating the labeling and tracking of biomolecules containing azide groups.
Erlotinib-d6 hydrochloride is a deuterium-labeled inhibitor of the epidermal growth factor receptor (EGFR) kinase, demonstrating potent inhibition with an IC50 of 2 nM. This compound serves as a valuable tool in chemical research, particularly in the study of EGFR-related signaling pathways in cancer. Additionally, Erlotinib-d6 hydrochloride features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating the labeling and tracking of biomolecules containing azide groups.
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