Erlotinib-d6 is a deuterated analog of Erlotinib, specifically targeting the epidermal growth factor receptor (EGFR) as a tyrosine kinase inhibitor. With an IC50 of 2 nM for human EGFR, it demonstrates potent inhibitory activity crucial for studying EGFR-mediated signaling pathways. As a click chemistry reagent, Erlotinib-d6 contains an alkyne functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) for applications in chemical biology and bioconjugation research.
Erlotinib-d6 is a deuterated analog of Erlotinib, specifically targeting the epidermal growth factor receptor (EGFR) as a tyrosine kinase inhibitor. With an IC50 of 2 nM for human EGFR, it demonstrates potent inhibitory activity crucial for studying EGFR-mediated signaling pathways. As a click chemistry reagent, Erlotinib-d6 contains an alkyne functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) for applications in chemical biology and bioconjugation research.
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