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Erlotinib HCl

Catalog No.: A10362

EGFR inhibitor

Erlotinib HCl

Erlotinib HCl Chemical Structure

CAS NO. 183319-69-9

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

Availability: In stock

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100 mg

Regular Price: $40.00

Special Price $32.00

500 mg

Regular Price: $80.00

Special Price $64.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yuta Yamamoto, .et al. Quantitative determination of erlotinib in human serum using competitive enzyme-linked immunosorbent assay, J Pharm Anal, 2018, Apr; 8(2): 119-123 PMID: 29736298
  • Aikawa S, .et al. Proliferation of mouse endometrial stromal cells in culture is highly sensitive to lysophosphatidic acid signaling, Biochem Biophys Res Commun, 2017, Feb 26;484(1):202-208 PMID: 28073697

Biological Activity

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
HER1/EGFR (Cell-free assay)
2 nM
In vitro (25°C) DMSO Warmed: 4 mg/mL (9.3 mM)
Water Insoluble
Ethanol Insoluble
In vivo 15% Captisol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.26 mL 116.31 mL 232.61 mL
0.5 mM 4.65 mL 23.26 mL 46.52 mL
1 mM 2.33 mL 11.63 mL 23.26 mL
5 mM 0.47 mL 2.33 mL 4.65 mL

*The above data is based on the productmolecular weight 429.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10362
Actions Inhibitor
CAS No. 183319-69-9
Formula C22H23N3O4.HCl
M. Wt 429.9
Purity >98%
Synonyms CP-358774, OSI-774, NSC 718781

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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