Erlotinib HCl

Catalog No.: A10362
EGFR inhibitor
Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
Grouped product items
Product Name Price Stock Qty
Erlotinib Hydrochloride 100mg
$40.00
In stock
Erlotinib Hydrochloride 500mg
$80.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Erlotinib HCl has been cited by 2 publications
  • Yuta Yamamoto, .et al. , J Pharm Anal, 2018, Apr; 8(2): 119-123 PMID: 29736298
  • Aikawa S, .et al. , Biochem Biophys Res Commun, 2017, Feb 26;484(1):202-208 PMID: 28073697
  • Biological Activity
    Discription Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
    Targets
    Target Value
    Product Information
    Catalog Num A10362
    Formula C22H23N3O4.HCl
    Molecular Weight 429.9
    CAS Number 183319-69-9
    SMILES COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
    Synonyms CP-358774, OSI-774, NSC 718781
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 4 mg/mL (9.3 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 15% Captisol 15 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.26 mL 116.31 mL 232.61 mL
    0.5 mM 4.65 mL 23.26 mL 46.52 mL
    1 mM 2.33 mL 11.63 mL 23.26 mL
    5 mM 0.47 mL 2.33 mL 4.65 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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