Erlotinib HCl

Catalog No.: A10362

EGFR inhibitor

Erlotinib HCl Chemical Structure

CAS NO. 183319-69-9

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

Availability: In stock

Package Price Qty
100 mg

Regular Price: $40.00

Special Price $32.00

500 mg

Regular Price: $80.00

Special Price $64.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
Targets
HER1/EGFR (Cell-free assay)
2 nM
In vitro (25°C) DMSO 3 mg/mL (6.97 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO, 0.5% CMC Na and 15% Captisol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.26 mL 116.31 mL 232.61 mL
0.5 mM 4.65 mL 23.26 mL 46.52 mL
1 mM 2.33 mL 11.63 mL 23.26 mL
5 mM 0.47 mL 2.33 mL 4.65 mL

*The above data is based on the productmolecular weight 429.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10362
Actions Inhibitor
M. Wt 429.9
Formula C22H23N3O4.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183319-69-9
Synonyms CP-358774, OSI-774, NSC 718781
SMILES COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl

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