EST73502 monohydrochloride acts as a selective μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, exhibiting Kis of 64 nM and 118 nM for each target, respectively. This compound is orally bioavailable and can effectively cross the blood-brain barrier. EST73502 demonstrates notable antinociceptive properties, making it a valuable tool for research into pain modulation and neurobiology.
EST73502 monohydrochloride acts as a selective μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, exhibiting Kis of 64 nM and 118 nM for each target, respectively. This compound is orally bioavailable and can effectively cross the blood-brain barrier. EST73502 demonstrates notable antinociceptive properties, making it a valuable tool for research into pain modulation and neurobiology.
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