Estramustine is an antineoplastic agent that exerts antimitotic activity by depolymerizing microtubules through binding to tubulin 1. It inhibits mitosis in DU 145 prostate cancer cells with an IC50 of approximately 16 μM and induces mitotic arrest in prostate tumor xenograft models, making it a valuable compound for prostate cancer research and therapy.
Estramustine is an antineoplastic agent that exerts antimitotic activity by depolymerizing microtubules through binding to tubulin 1. It inhibits mitosis in DU 145 prostate cancer cells with an IC50 of approximately 16 μM and induces mitotic arrest in prostate tumor xenograft models, making it a valuable compound for prostate cancer research and therapy.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
