Estrogen receptor modulator 6

Catalog No.: A85295
Estrogen Receptor β Agonist
Estrogen Receptor Modulator 6 is a selective agonist for Estrogen Receptor β, demonstrating a Ki value of 0.44 nM. With a 19-fold selectivity for ERβ over ERα (Ki = 8.4 nM), this compound enhances ERβ-mediated signaling, making it a valuable tool for studies in estrogen signaling pathways and related therapeutic research. Its selective action positions it as a potential candidate for investigating disorders influenced by estrogen receptor activity.
Grouped product items
Size Price Stock Qty
5mg
$4,205.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEstrogen Receptor Modulator 6 is a selective agonist for Estrogen Receptor β, demonstrating a Ki value of 0.44 nM. With a 19-fold selectivity for ERβ over ERα (Ki = 8.4 nM), this compound enhances ERβ-mediated signaling, making it a valuable tool for studies in estrogen signaling pathways and related therapeutic research. Its selective action positions it as a potential candidate for investigating disorders influenced by estrogen receptor activity.
Product Information
Catalog NumA85295
FormulaC18H16F2O3
Molecular Weight318.31
CAS Number787621-78-7
SMILESFC1(C[C@@]2([H])[C@](C1)([H])C3=CC(O)=CC=C3O[C@@]2([H])C4=CC=C(C=C4)O)F
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