Ethyl 1,4'-bipiperidine-4-carboxylate

Catalog No.: A84050
PROTAC Linker
Ethyl [1,4'-bipiperidine]-4-carboxylate serves as a PROTAC linker, facilitating the assembly of proteolysis-targeting chimeras (PROTACs). This compound enhances the delivery of ubiquitin ligases to targeted proteins, contributing to targeted protein degradation research. It is particularly useful in exploring therapeutic strategies for diseases driven by protein dysregulation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEthyl [1,4'-bipiperidine]-4-carboxylate serves as a PROTAC linker, facilitating the assembly of proteolysis-targeting chimeras (PROTACs). This compound enhances the delivery of ubiquitin ligases to targeted proteins, contributing to targeted protein degradation research. It is particularly useful in exploring therapeutic strategies for diseases driven by protein dysregulation.
Product Information
Catalog NumA84050
FormulaC13H24N2O2
Molecular Weight240.35
CAS Number344779-08-4
SMILESO=C(OCC)C1CCN(CC1)C2CCNCC2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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