EX 527 (Selisistat)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with IC50 of 38 nM in a cell-free assay. | ||
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Catalog Num | A10377 |
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Formula | C13H13ClN2O |
Molecular Weight | 248.7 |
CAS Number | 49843-98-3 |
SMILES | C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N |
Synonyms | EX527, EX-527 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 46 mg/mL (184.95 mM) | |
Water | Insoluble | ||
Ethanol | 17 mg/mL (68.35 mM) | ||
In vivo | 5% DMSO+30% PEG 300+ddH2O | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 40.21 mL | 201.05 mL | 402.09 mL |
0.5 mM | 8.04 mL | 40.21 mL | 80.42 mL |
1 mM | 4.02 mL | 20.1 mL | 40.21 mL |
5 mM | 0.8 mL | 4.02 mL | 8.04 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2