Exatecan
Important Notice: For research use only. We do not sell to patients.
Other Forms of Exatecan
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Important Notice: For research use only. We do not sell to patients.
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Discription | Exatecan inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. | ||
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Catalog Num | A11231 |
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Formula | C24H22FN3O4 |
Molecular Weight | 435.4554 |
CAS Number | 171335-80-1 |
SMILES | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O |
Synonyms | DX 8951, DX8951 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2