Ezetimibe (Zetia)

Catalog No.: A10379

Ezetimibe (Zetia)

Ezetimibe (Zetia) Chemical Structure

CAS NO. 163222-33-1

Ezetimibe is a compound that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. Ezetimibe localises at the brush border of the small intestine, where ezetimibe inhibits the absorption of cholesterol from the intestine.

Availability: In stock

Package Price Qty
25 mg

Regular Price: $40.00

Special Price $32.00

100 mg

Regular Price: $100.00

Special Price $80.00

10mM * 1mL in DMSO

Regular Price: $66.00

Special Price $52.80

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Nihei W, .et al. NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains, J Lipid Res, 2018, Nov; 59(11): 2181-2187 PMID: 30242108

Biological Activity

Ezetimibe is a compound that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. Ezetimibe localises at the brush border of the small intestine, where ezetimibe inhibits the absorption of cholesterol from the intestine.
In vitro (25°C) DMSO 75 mg/mL (183.19 mM)
Water Insoluble
Ethanol 75 mg/mL (183.19 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.43 mL 122.13 mL 244.26 mL
0.5 mM 4.89 mL 24.43 mL 48.85 mL
1 mM 2.44 mL 12.21 mL 24.43 mL
5 mM 0.49 mL 2.44 mL 4.89 mL

*The above data is based on the productmolecular weight 409.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10379
CAS No. 163222-33-1
Formula C24H21F2NO3
M. Wt 409.4
Purity >98%
Synonyms Zetia , Ezetrol
SMILES C1=CC(=CC=C1[[email protected]@H]2[[email protected]](C(=O)N2C3=CC=C(C=C3)F)CC[[email protected]@H](C4=CC=C(C=C4)F)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Ezetimibe (Zetia) | Ezetimibe (Zetia) Supplier | purchase | cost | manufacturer | order | distributor | buy 163222-33-1| 163222-33-1 Supplier | purchase 163222-33-1 | 163222-33-1 cost | 163222-33-1 manufacturer | order 163222-33-1 | 163222-33-1 distributor
Rewards