Ezetimibe (Zetia)

Name: Ezetimibe (Zetia)
Brand: Adooq Bioscience
SKU: A10379
Rating: 5 (2 reviews)

Catalog No.: A10379

Adooq's Ezetimibe (Zetia) has been cited by 2 publications

Ezetimibe is a compound that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. Ezetimibe localises at the brush border of the small intestine, where ezetimibe inhibits the absorption of cholesterol from the intestine.

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Grouped product items
Size	Price	Stock
5mg	$35.00	In stock
10mg	$35.00	In stock
25mg	$40.00	In stock
50mg	$65.00	In stock
100mg	$80.00	In stock
200mg	$120.00	In stock
500mg	$200.00	In stock
1g	$290.00	In stock
*10mM 1mL in DMSO**	$45.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Adooq's Ezetimibe (Zetia) has been cited by 2 publications

Yuki Ishii, .et al. , J Cell Sci, 2025, Apr 1;138(7):jcs263487 PMID: 40065746
Nihei W, .et al. , J Lipid Res, 2018, Nov; 59(11): 2181-2187 PMID: 30242108

Biological Activity

Description	Ezetimibe is a compound that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. Ezetimibe localises at the brush border of the small intestine, where ezetimibe inhibits the absorption of cholesterol from the intestine.

Product Information

Catalog Num	A10379
Formula	C24H21F2NO3
Molecular Weight	409.4
CAS Number	163222-33-1
SMILES	C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
Synonyms	Zetia , Ezetrol
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	75 mg/mL (183.19 mM)
	Water	Insoluble
	Ethanol	75 mg/mL (183.19 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.43 mL	122.13 mL	244.26 mL
0.5 mM	4.89 mL	24.43 mL	48.85 mL
1 mM	2.44 mL	12.21 mL	24.43 mL
5 mM	0.49 mL	2.44 mL	4.89 mL

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂