Fanotaprim is a selective inhibitor of dihydrofolate reductase (DHFR), demonstrating IC50 values of 1.57 nM for Toxoplasma gondii DHFR and 308 nM for human DHFR. This compound is particularly relevant for investigating toxoplasmosis, providing insight into potential therapeutic strategies against this parasitic infection. Its targeted inhibition of tgDHFR makes Fanotaprim a valuable tool for research in pharmacology and microbiology.
Fanotaprim is a selective inhibitor of dihydrofolate reductase (DHFR), demonstrating IC50 values of 1.57 nM for Toxoplasma gondii DHFR and 308 nM for human DHFR. This compound is particularly relevant for investigating toxoplasmosis, providing insight into potential therapeutic strategies against this parasitic infection. Its targeted inhibition of tgDHFR makes Fanotaprim a valuable tool for research in pharmacology and microbiology.
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