Fasiglifam hemihydrate is a potent and selective agonist of the GPR40 receptor, exhibiting an EC50 value of 72 nM. This compound enhances glucose-dependent insulin secretion and has demonstrated efficacy in reducing hyperglycemia in type 2 diabetic rat models. It is important to note that Fasiglifam may also induce liver injury, warranting careful consideration in research applications.
Fasiglifam hemihydrate is a potent and selective agonist of the GPR40 receptor, exhibiting an EC50 value of 72 nM. This compound enhances glucose-dependent insulin secretion and has demonstrated efficacy in reducing hyperglycemia in type 2 diabetic rat models. It is important to note that Fasiglifam may also induce liver injury, warranting careful consideration in research applications.
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