Fenspiride-d5 is a deuterium-labeled derivative of Fenspiride, an orally active non-steroidal anti-inflammatory agent. It functions primarily as an H1-histamine receptor antagonist and exhibits inhibitory activity against phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4), and phosphodiesterase 5 (PDE5), with -log IC50 values of 3.44, 4.16, and approximately 3.8, respectively. This reagent is valuable for investigating respiratory diseases and understanding the pharmacodynamics of its parent compound in biochemical research.
Fenspiride-d5 is a deuterium-labeled derivative of Fenspiride, an orally active non-steroidal anti-inflammatory agent. It functions primarily as an H1-histamine receptor antagonist and exhibits inhibitory activity against phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4), and phosphodiesterase 5 (PDE5), with -log IC50 values of 3.44, 4.16, and approximately 3.8, respectively. This reagent is valuable for investigating respiratory diseases and understanding the pharmacodynamics of its parent compound in biochemical research.
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