Fidarestat (SNK-860)

Catalog No.: A11790

Aldose reductase inhibitor

Fidarestat (SNK-860)

Fidarestat (SNK-860) Chemical Structure

CAS NO. 136087-85-9

Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.

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1 mg

Regular Price: $50.00

Special Price $40.00

5 mg

Regular Price: $200.00

Special Price $160.00

10 mg

Regular Price: $380.00

Special Price $304.00

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Biological Activity

Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.81 mL 179.07 mL 358.14 mL
0.5 mM 7.16 mL 35.81 mL 71.63 mL
1 mM 3.58 mL 17.91 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL

*The above data is based on the productmolecular weight 279.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11790
Actions Inhibitor
CAS No. 136087-85-9
Formula C12H10FN3O4
M. Wt 279.22
Purity >98%
Synonyms SNK 860, SNK-860
SMILES O=C1NC(N[[email protected]@]12C3=C(C=CC(F)=C3)O[[email protected]](C(N)=O)C2)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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