Aldose Reductase

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  1. aldose reductase inhibitor

    Epalrestat is an aldose reductase inhibitor.
  2. Aldose reductase inhibitor

    Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
  3. aldose reductase inhibitor

    Tolrestat is an aldose reductase inhibitor[1] which was approved for the control of certain diabetic complications.
  4. aldose reductase inhibitor

    Ranirestat is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.
  5. Aldose reductase inhibitor

    Sorbinil, is an Aldose reductase inhibitor (ARI).
  6. aldose reductase inhibitor

    Imirestat (AL 1576) is an aldose reductase inhibitor, used for the treatment of diabetes.
  7. aldose reductase inhibitor

    Aldose reductase-IN-1 is a inhibitor of aldose reductase with IC50 of 28.9 pM. IC50 value: 28.9 pM Target: aldose reductase Detailed information please refer to WO2014113380 A1 and US20130225592.
  8. aldose reductase inhibitor

    Risarestat (CT-112), an aldose reductase inhibitor, is developed for the treatment of diabetic complications
  9. aldose reductase inhibitor

    Ponalrestat, also known as MK-538, is an aldose reductase inhibitor.
  10. CNS penetrant Aldose Reductase inhibitor

    AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM. AT-007 reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.

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