Catalog No.
Product Name
Application
Product Information
Product Citation
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Aldose reductase inhibitor
Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. -
aldose reductase inhibitor
Ranirestat is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy. -
aldose reductase inhibitor
Aldose reductase-IN-1 is a inhibitor of aldose reductase with IC50 of 28.9 pM. IC50 value: 28.9 pM Target: aldose reductase Detailed information please refer to WO2014113380 A1 and US20130225592. -
aldose reductase inhibitor
Risarestat (CT-112), an aldose reductase inhibitor, is developed for the treatment of diabetic complications -
CNS penetrant Aldose Reductase inhibitor
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM. AT-007 reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.
