Fludarabine (Fludara)

Catalog No.: A10396

STAT inhibitor

Fludarabine (Fludara) Chemical Structure

CAS NO. 21679-14-1

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.

Availability: In stock

Package Price Qty
10 mg
$40.00
50 mg
$130.00
100 mg
$230.00
10mM * 1mL in DMSO
$70.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Targets
STAT1 (Vascular smooth muscle cells)
In vitro (25°C) DMSO 57 mg/mL (199.83 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.06 mL 175.32 mL 350.63 mL
0.5 mM 7.01 mL 35.06 mL 70.13 mL
1 mM 3.51 mL 17.53 mL 35.06 mL
5 mM 0.7 mL 3.51 mL 7.01 mL

*The above data is based on the productmolecular weight 285.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10396
Actions Inhibitor
M. Wt 285.2
Formula C10H12FN5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 21679-14-1
Synonyms F-ara-A, NSC 118218
SMILES OC[[email protected]@H]1O[[email protected]@H]([[email protected]@H]([[email protected]]1O)O)[[email protected]@H]1C=Nc2c1nc(F)nc2N

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