Flufenamic acid-13C6 is a stable isotope-labeled derivative of Flufenamic acid, a non-steroidal anti-inflammatory agent. It primarily targets cyclooxygenase (COX) and activates AMP-activated protein kinase (AMPK), while also modulating various ion channels, including chloride and L-type Ca2+ channels, and non-selective cation channels. Additionally, Flufenamic acid-13C6 binds to the central pocket of TEAD2 YBD, inhibiting TEAD function and impacting TEAD-YAP-dependent biological processes, such as cell migration and proliferation. This compound is valuable for metabolic studies and investigations into inflammatory pathways.
Flufenamic acid-13C6 is a stable isotope-labeled derivative of Flufenamic acid, a non-steroidal anti-inflammatory agent. It primarily targets cyclooxygenase (COX) and activates AMP-activated protein kinase (AMPK), while also modulating various ion channels, including chloride and L-type Ca2+ channels, and non-selective cation channels. Additionally, Flufenamic acid-13C6 binds to the central pocket of TEAD2 YBD, inhibiting TEAD function and impacting TEAD-YAP-dependent biological processes, such as cell migration and proliferation. This compound is valuable for metabolic studies and investigations into inflammatory pathways.
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