Fluorphine is a potent μ-opioid receptor (MOR) ligand that exhibits a binding affinity with a Ki value of 12.5 nM. This compound demonstrates biological activity by promoting GTPγS binding with an EC50 of 75 nM and facilitating β-arrestin 2 recruitment with an EC50 of 377 nM. Fluorphine is primarily used in research to investigate opioid signaling pathways and their physiological effects, including respiratory depression.
Fluorphine is a potent μ-opioid receptor (MOR) ligand that exhibits a binding affinity with a Ki value of 12.5 nM. This compound demonstrates biological activity by promoting GTPγS binding with an EC50 of 75 nM and facilitating β-arrestin 2 recruitment with an EC50 of 377 nM. Fluorphine is primarily used in research to investigate opioid signaling pathways and their physiological effects, including respiratory depression.
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