Fmoc-9-Aminononanoic acid functions as a PROTAC linker, featuring a terminal Fmoc-protected amine and a carboxylic acid group. This compound is instrumental in the synthesis of PROTACs and other conjugation applications. The Fmoc group is removable under basic conditions, yielding a free amine suitable for further conjugations. Additionally, the carboxylic acid can readily engage with primary amines in the presence of coupling agents such as EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical applications.
Fmoc-9-Aminononanoic acid functions as a PROTAC linker, featuring a terminal Fmoc-protected amine and a carboxylic acid group. This compound is instrumental in the synthesis of PROTACs and other conjugation applications. The Fmoc group is removable under basic conditions, yielding a free amine suitable for further conjugations. Additionally, the carboxylic acid can readily engage with primary amines in the presence of coupling agents such as EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical applications.
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