Fmoc-NH-PEG12-CH2CH2COOH

Catalog No.: A81536
PROTAC Linker
Fmoc-NH-PEG12-CH2CH2COOH is a polyethylene glycol (PEG) based linker designed for the development of PROTAC molecules. This compound facilitates the targeted degradation of proteins by promoting the formation of ternary complexes between E3 ligases and specified protein targets. Its application is crucial in biochemistry and pharmaceutical research focused on innovative therapeutic strategies that harness the ubiquitin-proteasome system for selective protein degradation.
Grouped product items
Size Price Stock Qty
25mg
$25.00
In stock
250mg
$30.00
In stock
1g
$95.00
In stock
5g
$420.00
In stock
10g
$830.00
In stock
25g
$1,655.00
In stock
100g
$5,475.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-NH-PEG12-CH2CH2COOH is a polyethylene glycol (PEG) based linker designed for the development of PROTAC molecules. This compound facilitates the targeted degradation of proteins by promoting the formation of ternary complexes between E3 ligases and specified protein targets. Its application is crucial in biochemistry and pharmaceutical research focused on innovative therapeutic strategies that harness the ubiquitin-proteasome system for selective protein degradation.
Product Information
Catalog NumA81536
FormulaC42H65NO16
Molecular Weight839.97
CAS Number1952360-91-6
SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2