Fmoc-NH-PEG25-CH2CH2COOH

Catalog No.: A83064
PROTAC Linker
Fmoc-NH-PEG25-CH2CH2COOH is a PEG-based linker specifically designed for PROTAC (Proteolysis Targeting Chimera) applications. This compound facilitates the conjugation of target proteins to E3 ligases, enhancing the selective degradation of proteins in cellular systems. It is particularly useful in the development of novel therapeutics aimed at regulating protein levels for research in cancer biology, neurodegeneration, and other disease models.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-NH-PEG25-CH2CH2COOH is a PEG-based linker specifically designed for PROTAC (Proteolysis Targeting Chimera) applications. This compound facilitates the conjugation of target proteins to E3 ligases, enhancing the selective degradation of proteins in cellular systems. It is particularly useful in the development of novel therapeutics aimed at regulating protein levels for research in cancer biology, neurodegeneration, and other disease models.
Product Information
Catalog NumA83064
FormulaC68H117NO29
Molecular Weight1412.65
CAS Number1257223-69-0
SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2