FR 180204

Catalog No.: A14119
ERK inhibitor
FR 180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.
Grouped product items
Product Name Price Stock Qty
FR 180204 10mg
$120.00
In stock
FR 180204 25mg
$250.00
In stock
FR 180204 50mg
$400.00
In stock
FR 180204 10mM * 1mL in DMSO
$95.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's FR 180204 has been cited by 2 publications
  • Sergey A Dyshlovoy, .et al. , Sci Rep, 2020, Aug 6;10(1):13178 PMID: 32764580
  • Dyshlovoy SA, .et al. , Proteomics, 2017, Jun;17(11) PMID: 28445005
  • Biological Activity
    Discription FR 180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.
    Targets
    Target Value
    Product Information
    Catalog Num A14119
    Formula C18H13N7
    Molecular Weight 327.34
    CAS Number 865362-74-9
    SMILES C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=CC5=C(NN=C5N=N4)N
    Synonyms FR-180204,FR180204
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 57 mg/mL (174.13 mM)
    Water Insoluble
    Ethanol Warmed: 2 mg/mL (6.1 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.55 mL 152.75 mL 305.49 mL
    0.5 mM 6.11 mL 30.55 mL 61.1 mL
    1 mM 3.05 mL 15.27 mL 30.55 mL
    5 mM 0.61 mL 3.05 mL 6.11 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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