FRAX597
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | FRAX597, a small-molecule pyridopyrimidinone, is a potent and ATP competitive inhibitor of the group I PAKs (PAK1 IC50= 8 nM, PAK2 IC50= 13 nM, PAK3 IC50= 19 nM). | ||
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Targets |
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Catalog Num | A12553 |
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Formula | C29H28ClN7OS |
Molecular Weight | 558.1 |
CAS Number | 1286739-19-2 |
SMILES | CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)C4=CN=CS4)Cl)NC5=CC=C(C=C5)N6CCN(CC6)C |
Synonyms | FRAX 597, FRAX-597 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 13 mg/mL (23.29 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (1.79 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.92 mL | 89.59 mL | 179.18 mL |
0.5 mM | 3.58 mL | 17.92 mL | 35.84 mL |
1 mM | 1.79 mL | 8.96 mL | 17.92 mL |
5 mM | 0.36 mL | 1.79 mL | 3.58 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2