G-479

Catalog No.: A14380

MEK inhibitor

G-479

G-479 Chemical Structure

CAS NO. 1168092-22-5

G-479 is an potent MEK inhibitor. G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.

Availability: In stock

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2 mg
$200.00
5 mg
$450.00
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Biological Activity

G-479 is an potent MEK inhibitor. G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.52 mL 102.62 mL 205.25 mL
0.5 mM 4.1 mL 20.52 mL 41.05 mL
1 mM 2.05 mL 10.26 mL 20.52 mL
5 mM 0.41 mL 2.05 mL 4.1 mL

*The above data is based on the productmolecular weight 487.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14380
Actions Inhibitor
CAS No. 1168092-22-5
Formula C16H15FIN5O4
M. Wt 487.22
Purity >98%
Synonyms G479, G 479
SMILES O=C(C1=C(NC2=CC=C(I)C=C2F)N3C(C=N1)=CN=C3)NOC[[email protected]](O)CO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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