Fig. 1 · Structure

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γ1-MSH

MC3 Receptor Agonist

γ1-MSH is an agonist of the melanocortin MC3 receptor, exhibiting a Ki of 34 nM for the rat MC3 receptor. This compound demonstrates approximately 40-fold selectivity over the MC4 receptor, with a Ki of 1318 nM. γ1-MSH is valuable for research applications exploring the role of melanocortin receptors in metabolic processes and neuroendocrine regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 72629-65-3
Applications MC3 Receptor Agonist
Formula C72H97N21O14S
Molecular Weight 1512.74
SMILES
C([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)[C@@H](C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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