GDC-0980 (Apitolisib, RG7422)

GDC-0980 (RG7422) is a selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2) with in vitro IC50 of 5, 27, 7 and 14 nM for p110 α, β, δ and γ isoforms, respectively.
Grouped product items
Product Name Price Stock Qty
GDC-0980 5mg
$60.00
In stock
GDC-0980 10mg
$100.00
In stock
GDC-0980 50mg
$260.00
In stock
GDC-0980 100mg
$440.00
In stock
GDC-0980 (RG7422) 10mM * 1mL in DMSO
$75.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's GDC-0980 (Apitolisib, RG7422) has been cited by 1 publications
  • Kasun Wanigasooriya, .et al. , Front Oncol, 2022, Jul 4;12:920444 PMID: 35860583
  • Biological Activity
    Discription GDC-0980 (RG7422) is a selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2) with in vitro IC50 of 5, 27, 7 and 14 nM for p110 α, β, δ and γ isoforms, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A11023
    Formula C23H30N8O3S
    Molecular Weight 498.6
    CAS Number 1032754-93-0
    SMILES CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)C(=O)[C@H](C)O
    Synonyms GDC0980
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 20 mg/mL (40.11 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% methylcellulose+0.2% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.06 mL 100.28 mL 200.56 mL
    0.5 mM 4.01 mL 20.06 mL 40.11 mL
    1 mM 2.01 mL 10.03 mL 20.06 mL
    5 mM 0.4 mL 2.01 mL 4.01 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy GDC-0980 (Apitolisib, RG7422) | GDC-0980 (Apitolisib, RG7422) Supplier | purchase GDC-0980 (Apitolisib, RG7422) | GDC-0980 (Apitolisib, RG7422) cost | GDC-0980 (Apitolisib, RG7422) manufacturer | order GDC-0980 (Apitolisib, RG7422) | GDC-0980 (Apitolisib, RG7422) distributor | buy 1032754-93-0 | 1032754-93-0 Supplier | purchase 1032754-93-0 | 1032754-93-0 cost | 1032754-93-0 manufacturer | order 1032754-93-0 | 1032754-93-0 distributor