Gefapixant
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Gefapixant is an orally active P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. |
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Catalog Num | A19254 |
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Formula | C14H19N5O4S |
Molecular Weight | 353.4 |
CAS Number | 1015787-98-0 |
SMILES | O=S(C1=CC(OC2=CN=C(N)N=C2N)=C(C(C)C)C=C1OC)(N)=O |
Synonyms | AF219, AF 219, AF-219; MK-7264, MK7264, MK 7264 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 65 mg/mL (183.92 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.3 mL | 141.48 mL | 282.97 mL |
0.5 mM | 5.66 mL | 28.3 mL | 56.59 mL |
1 mM | 2.83 mL | 14.15 mL | 28.3 mL |
5 mM | 0.57 mL | 2.83 mL | 5.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2