GLPG0634

Catalog No.: A13162

JAK1 inhibitor

GLPG0634 Chemical Structure

CAS NO. 1206101-20-3

GLPG0634 is an orally-available, selective inhibitor of JAK1 (Janus kinase 1) being developed by Galapagos for the treatment of rheumatoid arthritis and potentially other inflammatory diseases.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $200.00

Special Price $160.00

10 mg

Regular Price: $350.00

Special Price $280.00

25 mg

Regular Price: $680.00

Special Price $544.00

50 mg

Regular Price: $1,100.00

Special Price $880.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GLPG0634 is an orally-available, selective inhibitor of JAK1 (Janus kinase 1) being developed by Galapagos for the treatment of rheumatoid arthritis and potentially other inflammatory diseases.
Targets
JAK
In vitro DMSO 0.1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.38 mL 121.91 mL 243.81 mL
0.5 mM 4.88 mL 24.38 mL 48.76 mL
1 mM 2.44 mL 12.19 mL 24.38 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 410.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13162
Actions Inhibitor
M. Wt 410.15
Formula C23H18N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1206101-20-3
Synonyms GLPG 0634, GLPG-0634
SMILES c1cc(n2c(c1)nc(n2)NC(=O)C3CC3)c4ccc(cc4)OCc5ccc(nc5)C#N

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