Glucosylceramide synthase-IN-3

Name: Glucosylceramide synthase-IN-3
Brand: Adooq Bioscience
SKU: A78938
Rating: 5 (288 reviews)

Catalog No.: A78938

GCS Inhibitor

Glucosylceramide synthase-IN-3 is a potent inhibitor of glucosylceramide synthase (GCS), demonstrating an IC50 of 16 nM for human GCS. This compound is brain-penetrant and orally active, making it suitable for in vivo studies. Glucosylceramide synthase-IN-3 is primarily used in research focused on Gaucher's disease and related glycosphingolipid metabolism disorders.

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Glucosylceramide synthase-IN-3 3029827-91-3 GCS Inhibitor

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Grouped product items
Size	Price	Stock
5mg	$535.00	In stock
10mg	$880.00	In stock
25mg	$1,765.00	In stock
50mg	$2,790.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Glucosylceramide synthase-IN-3 is a potent inhibitor of glucosylceramide synthase (GCS), demonstrating an IC50 of 16 nM for human GCS. This compound is brain-penetrant and orally active, making it suitable for in vivo studies. Glucosylceramide synthase-IN-3 is primarily used in research focused on Gaucher's disease and related glycosphingolipid metabolism disorders.

Product Information

Catalog Num	A78938
Formula	C21H20FN3O3
Molecular Weight	381.40
CAS Number	3029827-91-3
SMILES	O=C(O[C@H]1CN2CCC1CC2)NC3=CC=CC4=C3N=C(O4)C5=CC=C(C=C5)F

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